Pemphigus Foliaceus in Horses

Treatment of Pemphigus Foliaceus consists of long-term glucocorticoid administration, omega fatty acid and vitamin E supplementation, sunlight restriction, and addressing any underlying causative factors such as fly bite allergies and diet.
Horses that do not respond to these approaches might require treatment with injectable gold salts, azathioprine, and/or oral pentoxifylline. Bathing the horse in cool water might make him more comfortable.
Rarely, young horses with PF might recover on their own, but most horses will require long-term if not lifelong treatment.